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Image Search Results
Journal: PLoS ONE
Article Title: Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats
doi: 10.1371/journal.pone.0178796
Figure Lengend Snippet: Surface plasmon resonance analysis showing binding of purified human cysC to immobilized megalin (A) and cubilin (B) at dilutions ranging from 20 nM to 500 nM. The calculated Kd was approximately 32 nM for binding to megalin and 24 nM for binding to cubilin. In (C) and (D) the flow of cystatin C (150 nM) was preceded by binding of RAP (5 μM) essentially abolishing the binding to megalin (C) and cubilin (D).
Article Snippet:
Techniques: SPR Assay, Binding Assay, Purification